科學家總結全身麻醉的神經網絡機制
作者:小柯機器人 發布時間:2024/8/25 12:41:24
本期文章:《神經科學通報》:Online/在線發表
復旦大學王英偉等研究人員合作總結全身麻醉的神經網絡機制——皮層與皮層下核團的作用。該研究于2024年8月21日在線發表于國際一流學術期刊《神經科學通報》。
研究人員總結了當前關于皮層和皮層下核團在調節全身麻醉中的作用的理解,提供與麻醉和意識相關的皮層-皮層和丘腦-皮層網絡的新證據。這些見解有助于全面理解全身麻醉背后的神經網絡機制。
據悉,全身麻醉在現代醫學中具有重要作用,但其精確的機制仍然不清楚,構成了麻醉學中的一個關鍵科學挑戰。神經科學技術的進步使得對特定神經回路的靶向操作和捕捉全腦神經活動的高分辨率成為可能,這為闡明全身麻醉藥物的復雜作用機制帶來了希望。
附:英文原文
Title: Neural Network Mechanisms Underlying General Anesthesia: Cortical and Subcortical Nuclei
Author: Hu, Yue, Wang, Yun, Zhang, Lingjing, Luo, Mengqiang, Wang, Yingwei
Issue&Volume: 2024-08-21
Abstract: General anesthesia plays a significant role in modern medicine. However, the precise mechanism of general anesthesia remains unclear, posing a key scientific challenge in anesthesiology. Advances in neuroscience techniques have enabled targeted manipulation of specific neural circuits and the capture of brain-wide neural activity at high resolution. These advances hold promise for elucidating the intricate mechanisms of action of general anesthetics. This review aims to summarize our current understanding of the role of cortical and subcortical nuclei in modulating general anesthesia, providing new evidence of cortico-cortical and thalamocortical networks in relation to anesthesia and consciousness. These insights contribute to a comprehensive understanding of the neural network mechanisms underlying general anesthesia.
DOI: 10.1007/s12264-024-01286-z
Source: https://link.springer.com/article/10.1007/s12264-024-01286-z
期刊信息
Neuroscience Bulletin:《神經科學通報》,創刊于2006年。隸屬于施普林格·自然出版集團,最新IF:5.6
官方網址:https://link.springer.com/journal/12264
投稿鏈接:https://mc03.manuscriptcentral.com/nsb



